Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP.
May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects.
May regulate diuresis, blood pressure and skeletal development.
Does not have guanylate cyclase activity (By similarity).
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity:Recognizes rat Npr3.
Isotype:IgG
Calc Applications Abbrev:E
Calc Crossreactivity:Rt
Immunogen:Recombinant protein corresponding to aa41-477 from rat Atrial natriuretic peptide receptor 3 protein.