Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP.
Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency.
Cannot use triazofurin monophosphate (TrMP) as substrate.
Also catalyzes the reverse reaction, i.e.
the pyrophosphorolytic cleavage of NAD(+).
For the pyrophosphorolytic activity prefers NAD(+), NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively.
Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+).
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human NMNAT2.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to human aa1-153 from Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 protein.
