Stress-responsive protein involved in hormone responses, cell growth, anddifferentiation.
Acts as a tumor suppressor in many cell types.
Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis.
Has a role in cell trafficking, notably of the Schwann cell, and is necessary for the maintenance and development of the peripheral nerve myelin sheath.
Required for vesicular recycling of CDH1 and TF.
May also function in lipid trafficking.
Protects cells from spindle disruption damage.
Functions in p53/TP53- dependent mitotic spindle checkpoint.
Heat antigen retrieval is required using citrate buffer, pH 6.0
Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol
Specificity:Recognizes human NDRG1
Isotype:IgG
Calc Applications Abbrev:E IF IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to aa136-394 of human NDRG1. Subcellular Location: Cytoplasm, cytosol, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Nucleus, Cell membrane