Plays a role in the maintenance of the undifferentiated state of germ cellsregulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase.
Affects cell proliferation probably by repressing translation of specific mRNAs.
Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways.
Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
Applications:Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:20-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human NANOS3.
Isotype：IgG
Calc Applications Abbrev：E IF IHC
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to aa21-192 from human Nanos homolog 3 protein.
