Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses.
Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid.
May also antagonize reoviridae and asfarviridae replication.
Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids.
Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress.
Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles.
Enhances ER stress-mediated cell death after influenza virus infection.
May regulate the calcium channel activity of TRPCs.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Immunoprecipitation.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000-1:5000Immunohistochemistry: 1:20-1:200Immunofluorescence: 1:50-1:200Immunohistochemistry: 1:200-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human MX1. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IF IHC IP WB
Calc Crossreactivity：Hu Mo
Immunogen：Recombinant protein corresponding to aa7-172 from human Interferon-induced GTP-binding protein Mx1 protein.
