May play a role in RNA metabolism in both nuclei and mitochondria.
In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export.
May bind mature mRNA in the nucleus outer membrane.
In mitochondria binds to poly(A) mRNA.
Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits.
May be involved in transcription regulation.
Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors.
Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP.
Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters.
Binds single-stranded DNA (By similarity).
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Biotin.
Specificity：Recognizes human LRPPRC.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to aa901-1036 from human leucine-rich PPR motif-containing protein, mitochondrial protein.
