84-5933-52 L1 (FITC) 50ug 566869
特徴
- Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.
- The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.
- Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.
- This binding mediates a conformational change in the virus capsid that facilitates efficient infection.
- The virion enters the host cell via endocytosis.
- During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.
- The virion assembly takes place within the cell nucleus.
- Encapsulates the genomic DNA together with protein L2.
- Applications:Suitable for use in FLISA.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
- For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
- Aliquots are stable at -20°C for 12 months after receipt.
- Dilute required amount only prior to immediate use.
- Further dilutions can be made in assay buffer.
- Caution: FITC conjugates are sensitive to light.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by Protein G affinity chromatography.
- Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Fluorescein isothiocyanate (FITC).
- Specificity:Recognizes human L1.
- Isotype:IgG
- Calc Applications Abbrev:FLISA
- Calc Crossreactivity:Hu
- Immunogen:Recombinant protein corresponding to aa6-471 from human papillomavirus type 16 major capsid protein L1.
- Shelf Life:1year
- Swiss Prot Number:P03101
- EU Commodity Code:30021010
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