84-5921-53　KCNMB3 (Biotin) 100ul　566275

特徴

• Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel.
• Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.
• Alters the functional properties of the current expressed by the KCNMA1 channel.
• Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA.
• Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations.
• In contrast, isoform 1 does not induce detectable inactivation of KCNMA1.
• Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer.
• Applications:Suitable for use in ELISA.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.