84-5921-50 KCNMB3 50ul 566274
特徴
- Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK)channel.
- Modulates the calcium sensitivity and gating kinetics of KCNMA1,thereby contributing to KCNMA1 channel diversity.
- Alters the functionalproperties of the current expressed by the KCNMA1 channel.
- Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA.
- Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations.
- In contrast, isoform 1 does not induce detectable inactivation of KCNMA1.
- Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer.
- Applications:Suitable for use in ELISA and Immunofluorescence.
- Other applications not tested.
- Recommended Dilutions:Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：50ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography
- Form：Supplied as a liquid in PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol
- Specificity：Recognizes human KCNMB3.
- Isotype：IgG
- Calc Applications Abbrev：E IF
- Calc Crossreactivity：Hu
- Immunogen：Recombinant protein corresponding to aa82-207 of human KCNMB3. Subcellular Location: Membrane, Multi-pass membrane protein
- Shelf Life：1year
- Swiss Prot Number：Q9NPA1
- EU Commodity Code：30021010
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