Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats.
Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actindestabilizing cytochalasin B when overexpressed.
Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity).
May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein.
Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasingthe concentration of AHR available to activate transcription.
Applications:Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence.
Heat antigen retrieval is required using citrate buffer, pH 6.0
Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography
Form：Supplied as a liquid in PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol
Specificity：Recognizes human IVNS1ABP
Isotype：IgG
Calc Applications Abbrev：E IF IHC
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to aa401-642 of human human IVNS1ABP. Subcellular Location: Cytoplasm, Cytoplasm, cytoskeleton, Nucleus, Nucleoplasm
