84-5915-21　ITGA4 (Biotin) 100ug　565962

特徴

• Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin.
• They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin.
• They are also receptors for VCAM1.
• Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1.
• Integrin alpha-4/beta-7 is also a receptor for MADCAM1.
• It recognizes the sequence L-D-T in MADCAM1.
• On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines.
• It may also participate in cytolytic T-cell interactions with target cells.
• ITGA4.
• Applications:Suitable for use in ELISA.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.