Receptor for IL17A (PubMed:17911633, PubMed:9367539).
Receptor for IL17F (PubMed:19838198, PubMed:17911633).
Binds to IL17A with higher affinity than to IL17F (PubMed:17911633).
Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (PubMed:16785495).
Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC (PubMed:18684971).
Receptor for IL17C as part of a heterodimericcomplex with IL17RE (PubMed:21993848).
Activation of IL17RA leads toinduction of expression of inflammatory chemokines and cytokines such asCXCL1, CXCL8/IL8 and IL6 (PubMed:16785495, PubMed:17911633,PubMed:18684971).
Applications:Suitable for use in ELISA, Western Blot and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:5000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human IL17RA. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IF WB
Calc Crossreactivity：Hu Mo
Immunogen：Recombinant protein corresponding to aa552-743 from human Interleukin-17 receptor A protein.
