Transcription regulator of hematopoietic cell differentiation (PubMed:17934067).
Binds gamma-satellite DNA (PubMed:17135265, PubMed:19141594).
Plays a role in the development of lymphocytes, B- and T-cells.
Binds and activates the enhancer (delta-A element) of the CD3-delta gene.
Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocytedifferentiation.
Regulates transcription through association with both HDACdependent and HDAC-independent complexes.
Targets the 2 chromatinremodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes.
Increases normal apoptosis in adult erythroid cells.
Confers early temporal competence to retinal progenitor cells (RPCs).
Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed:17135265, PubMed:17934067).
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human IKZF1.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to aa1-265 from human DNA-binding protein Ikaros protein.
