84-5891-64　HIPK3 (HRP) 50ug　564796

特徴

• Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression.
• Phosphorylates JUN and RUNX2.
• Seems to negatively regulate apoptosis by promoting FADD phosphorylation.
• Enhances androgen receptor-mediated transcription.
• May act as a transcriptional corepressor for NK homeodomain transcription factors.
• The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
• In osteoblasts, supports transcription activation.
• Applications:Suitable for use in ELISA.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.