Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer.
Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation.
This is one of the isozymes catalyzing that reaction.
Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate (By similarity).
Applications:Suitable for use in ELISA and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity:Recognizes human HAS1.
Isotype:IgG
Calc Applications Abbrev:E IF
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to aa151-271 from human hyaluronan synthase 1 protein.