84-5854-06　FOXL2 (FITC) 100ug　562935

特徴

• Transcriptional regulator.
• Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination.
• Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity).
• Has apoptotic activity in ovarian cells.
• Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity).
• Is a regulator of CYP19 expression (By similarity).
• Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity).
• Is a transcriptional repressor of STAR.
• Activates SIRT1 transcription under cellular stress conditions.
• Activates transcription of OSR2.
• Applications:Suitable for use in FLISA.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.