84-5823-97 EMD (HRP) 100ug 561446
特徴
- Stabilizes and promotes the formation of a nuclear actin cortical network.
- Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments.
- Inhibits beta-catenin activity by preventing its accumulation in the nucleus.
- Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway.
- Links centrosomes to the nuclear envelope via a microtubule association.
- EMD and BAF are cooperative cofactors of HIV-1 infection.
- Association of EMD with the viral DNA requires the presence of BAF and viral integrase.
- The association of viral DNA with chromatin requires the presence of BAF and EMD.
- Required for proper localization of non-farnesylated prelamin-A/C.
- Applications:Suitable for use in ELISA.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
- For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
- Aliquots are stable at -20°C for 12 months after receipt.
- Dilute required amount only prior to immediate use.
- Further dilutions can be made in assay buffer.
- Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by Protein G affinity chromatography.
- Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with horseradish peroxidase (HRP).
- Specificity:Recognizes human EMD.
- Isotype:IgG
- Calc Applications Abbrev:E
- Calc Crossreactivity:Hu
- Immunogen:Recombinant protein corresponding to aa1-222 from human emerin.
- Shelf Life:1year
- Swiss Prot Number:P50402
- EU Commodity Code:30021010
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