Stabilizes and promotes the formation of a nuclear actin cortical network
Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments.
Inhibits beta-catenin activity by preventing its accumulation in the nucleus.
Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway.
Links centrosomes to the nuclear envelope via a microtubule association.
EMD and BAF are cooperative cofactors of HIV-1 infection.
Association of EMD with the viral DNA requires the presence of BAF and viral integrase.
The association of viral DNA with chromatin requires the presence of BAF and EMD.
Required for proper localization of non-farnesylated prelamin-A/C.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Immunoprecipitation.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:5000Immunohistochemistry: 1:20-1:200Immunofluorescence: 1:50-1:200Immunoprecipitation: 1:200-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human EMD. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IF IHC IP WB
Calc Crossreactivity：Hu Mo
Immunogen：Recombinant protein corresponding to aa1-222 from human Emerin protein.
