84-5809-31 DOCK10 (HRP) 100ug 560720
特徴
- Guanine nucleotide-exchange factor (GEF) that activates CDC42 and RAC1 by exchanging bound GDP for free GTP.
- Essential for dendritic spine morphogenesis in Purkinje cells and in hippocampal neurons, via a CDC42-mediated pathway.
- Sustains B-cell lymphopoiesis in secondary lymphoid tissues and regulates FCER2/CD23 expression.
- Applications:Suitable for use in ELISA.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
- For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
- Aliquots are stable at -20°C for 12 months after receipt.
- Dilute required amount only prior to immediate use.
- Further dilutions can be made in assay buffer.
- Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by Protein G affinity chromatography.
- Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with horseradish peroxidase (HRP).
- Specificity:Recognizes human DOCK10.
- Isotype:IgG
- Calc Applications Abbrev:E
- Calc Crossreactivity:Hu
- Immunogen:Recombinant protein corresponding to aa1645-2186 from human dedicator of cytokinesis protein 10.
- Shelf Life:1year
- Swiss Prot Number:Q96BY6
- EU Commodity Code:30021010
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