84-5805-21　DLX5 (FITC) 100ug　560517

特徴

• Transcriptional factor involved in bone development.
• Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation.
• Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation.
• Stimulates SP7 promoter activity during osteoblast differentiation.
• Promotes cell proliferation by up-regulating MYC promoter activity.
• Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton.
• Binds to the homeodomain-response element of the ALPL and SP7 promoter.
• Binds to the MYC promoter.
• Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.
• Applications:Suitable for use in FLISA.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.