Required for perception of chronic pain through NMDA receptor signaling.
Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord.
Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels.
Involved in regulation of synaptic stability at cholinergic synapses.
Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:5000Immunohistochemistry: 1:20-1:200Immunofluorescence: 1:200-1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity:Recognizes human DLG2. Species Crossreactivity: rat
Isotype:IgG
Calc Applications Abbrev:E IF IHC WB
Calc Crossreactivity:Hu Rt
Immunogen:Recombinant protein corresponding to aa310-420 from human disks large homolog 2 protein.