84-5796-41　DCSTAMP (Biotin) 50ug　560082

特徴

• Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis.
• Plays a role in TNFSF11-mediated osteoclastogenesis.
• Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs).
• Participates in osteoclast bone resorption.
• Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors.
• Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage.
• Inhibits the development of neutrophilic granulocytes.
• Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity.
• Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.
• Applications:Suitable for use in ELISA.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.