84-5796-39　DCSTAMP 50ug　560081

特徴

• Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis.
• Plays a role in TNFSF11-mediated osteoclastogenesis.
• Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs).
• Participates in osteoclast bone resorption.
• Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors.
• Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage.
• Inhibits the development of neutrophilic granulocytes.
• Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity.
• Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.
• Applications:Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: 1:200-1:500Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.