84-5757-13　CDK5RAP2 100ug　558137

特徴

• Potential regulator of CDK5 activity via its interaction with CDK5R1.
• Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion.
• Involved in regulation of mitotic spindle orientation (By similarity).
• Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter.
• Together with MAPRE1, it may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends.
• Regulates centrosomal maturation by recruitment of a gamma-tubulin ring complex onto centrosomes.
• Applications:Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: 1:20-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.