84-5752-79 CD47 (FITC) 50ug 557923
特徴
- Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins.
- Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity).
- Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.
- Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
- May play a role in membrane transport and/or integrin dependent signal transduction.
- May prevent premature elimination of red blood cells.
- May be involved in membrane permeability changes induced following virus infection.
- Applications:Suitable for use in FLISA.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
- For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
- Aliquots are stable at -20°C for 12 months after receipt.
- Dilute required amount only prior to immediate use.
- Further dilutions can be made in assay buffer.
- Caution: FITC conjugates are sensitive to light.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by Protein G affinity chromatography.
- Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Fluorescein isothiocyanate (FITC).
- Specificity:Recognizes human CD47.
- Isotype:IgG
- Calc Applications Abbrev:FLISA
- Calc Crossreactivity:Hu
- Immunogen:Recombinant protein corresponding to aa44-141 from human leukocyte surface antigen CD47.
- Shelf Life:1year
- Swiss Prot Number:Q08722
- EU Commodity Code:30021010
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