May act as a scaffolding protein within caveolar membranes.
Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation.
The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells.
Positive regulator of cellular mitogenesis of the MAPK signaling pathway.
Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
Applications:Suitable for use in FLISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:Recognizes human CAV2.
Isotype:IgG
Calc Applications Abbrev:FLISA
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to aa3-64 from human Caveolin-2.