Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle.
This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER.
Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity).
Involved in maternal gene expression regulation.
May participate in oocyte maturation via the regulation of calcium homeostasis.
Applications:Suitable for use in FLISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：porcine
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Fluorescein isothiocyanate (FITC).
Specificity：Recognizes porcine CALR.
Isotype：IgG
Calc Applications Abbrev：FLISA
Calc Crossreactivity：Po
Immunogen：Recombinant protein corresponding to aa18-417 from porcine calreticulin.
