84-5722-63　BHLHA15 (Biotin) 50ug　556430

特徴

• Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated.
• Repression may occur through muscle-specific E-box occupancy by homodimers.
• May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain.
• Serves as a key regulator of acinar cell function, stability, and identity.
• Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport.
• May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages.
• Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity).
• Applications:Suitable for use in ELISA.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.