Plays fundamental roles in nuclear assembly, chromatin organization, geneexpression and gonad development.
May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly.
Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging.
Exploited by retroviruses for inhibiting selfdestructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome.
EMD and BAF are cooperative cofactors of HIV-1 infection.
Association of EMD with the viral DNA requires the presence of BAF and viral integrase.
The association of viral DNA with chromatin requires the presence of BAF and EMD.
Applications:Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:20-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human BANF1.
Isotype：IgG
Calc Applications Abbrev：E IF IHC
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to aa2-89 from human barrier-to-autointegration factor protein.
