Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins.
Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling.
Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex.
Plays a role in neurite growth.
Acts syngeristically with ENAH to promote filipodia formation.
Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.
Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Western Blot: 1:200-1:5000Immunohistochemistry: 1:20-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human BAIAP2. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Recombinant protein corresponding to aa123-368 from human brain-specific angiogenesis inhibitor 1-associated protein 2.
