May mediate transcription activation by binding to the E box-containing promoter (By similarity).
Involved in neurogenesis.
Required for the development of neurons in the epiphysis, acting partially redundantly with neurog1 and downstream of flh.
Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression.
Also involved in pituitary development; required cell-autonomously in adenohypophyseal cells for endocrine differentiation and for survival of a subset of cells.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:Zebrafish
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity:Recognizes zebrafish ascl1a.
Isotype:IgG
Calc Applications Abbrev:E
Immunogen:Recombinant protein corresponding to aa1-196 from zebrafish ascl1a.