84-5688-79　AIMP1 (FITC) 50ug　554755

特徴

• Non-catalytic component of the multisynthase complex.
• Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase.
• Binds tRNA.
• Possesses inflammatory cytokine activity.
• Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation.
• Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels.
• Promotes dermal fibroblast proliferation and wound repair.
• Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum.
• Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations.
• Induces maturation of dendritic cells and monocyte cell adhesion.
• Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
• Applications:Suitable for use in FLISA.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.