Non-catalytic component of the multisynthase complex.
Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase.
Binds tRNA.
Possesses inflammatory cytokine activity.
Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation.
Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels.
Promotes dermal fibroblast proliferation and wound repair.
Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum.
Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations.
Induces maturation of dendritic cells and monocyte cell adhesion.
Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000-1:5000Immunohistochemistry: 1:20-1:200Immunoprecipitation: 1:200-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human AIMP1.
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to aa25-180 from human aminoacyl tRNA synthase complex-interacting multifunctional protein 1.
