84-5688-06　AHR (Biotin) 100ug　554718

特徴

• Ligand-activated transcriptional activator.
• Binds to the XRE promoter region of genes it activates.
• Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene).
• Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons.
• Involved in cell-cycle regulation.
• Likely to play an important role in the development and maturation of many tissues.
• Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1.
• Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
• Applications:Suitable for use in ELISA.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.