84-5688-03　AHR 50ug　554717

特徴

• Ligand-activated transcriptional activator.
• Binds to the XRE promoter region of genes it activates.
• Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene).
• Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons.
• Involved in cell-cycle regulation.
• Likely to play an important role in the development and maturation of many tissues.
• Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1.
• Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
• Applications:Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: 1:20-1:200Immunoflourescence: 1:50-1:200Optimal dilutions to be determined by the research
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.