Grp78 (Glucose Regulated 78kDa Protein), is also known as BiP or Immunoglobulin heavy chain binding protein.
It is a stressresponse protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function.
This protein is essential for the proper glycosylation, folding, and assembly of many membrane bound and secreted proteins as well as for maintenance of cell homeostasis and the prevention of apoptosis.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity:Recognizes rat Grp78/BiP. Species Crossreactivity: mouse, bovine, fungus, hamster, monkey, rabbit and xenopus.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Bo Hm Hu Mk Mo Rb Xe
Immunogen:Synthetic peptide corresponding to rat Grp78 (BiP) at C-terminal.Grp The sequence is completely conserved in mouse and hamster.