Chromogranin A (CgA) is a prohormone which is proteolytically processed in neurons prior to axonal transport.
The differential expression of chromogranin A fragments in neuronal populations suggests distinct functional roles for each CgA-derived peptide.
Immunohistochemical localization of CgA has been used as a marker for the identification and prognostic assessment of neuroendocrine tumors and CgA has also been reported to be a component of senile plaques in the brains of demented individuals.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:sheep
Source Antibody:human
Grade:Affinity Purified
Purity:Purified
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human chromogranin A
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Bo Ca Eq Mo Po Rt
Immunogen:Synthetic peptide corresponding to aa1-15, L1PVNSPMNKGDTEVM15, of native human chromogranin A, conjugated to KLH. Species sequence homology: bovine, chimpanzee, canine, equine, porcine, mouse and rat.