Pitx3, the third member of the Pitx family, is expressed in the eyes and in only one population of neurons, the dopaminergic neurons of the midbrain.
In human, mutations of the Pitx3 gene have been associated with a familial form of cataracts, which is consistent with one of the developmental roles of this gene.
Pitx3 expression in the midbrain starts just before terminal differentiation of dopaminergic neurons.
This temporal expression is consistent with a role of Pitx3 in the differentiation and/or maintenance of these neurons.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:200-1:1000 (ECL)Immunohistochemistry: 1:200-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4. No preservative added.
Specificity：Recognizes human Ptx3. Species Crossreactivity: rodent.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Rd
Immunogen：Synthetic peptide corresponding to human PTX3.
