84-5667-34　Enkephalin, Prepro (ppENK) 50ul　551598

特徴

• Met-enkephalin (tyr-gly-gly-phe-met) and leu-enkephalin (tyr-gly-gly-phe-leu) are pentapeptides which compete with and mimic the effects of opiate drugs.
• Although interest in enkephalins stems largely from their possible role in the brain, the richest source of these peptides is the adrenal gland.
• The amino acid sequence shows that the precursor is 267 amino acids long and contains 6 interspersed Met-enkephalin sequences and 1 Leu-enkephalin sequence.
• The precursor does not contain the sequences of dynorphin, alpha-neo-endorphin or beta-endorphin.
• (Because of structural similarities it had been postulated that beta-endorphin is precursor of Met-enkephalin, and that dynorphin or alpha-neo-endorphin is precursor of Leu-enkephalin.) It is involved in the modulation of nociceptive pain.
• ppENK may be capable of enhancing immune function in cancer or AIDS patients.
• Enkephalin is one of several naturally occurring morphine-like substances released from nerve endings of the central nervous system and the adrenal medulla.
• Enkephalins act as analgesics and sedatives in the body and appear to affect mood and motivation.
• Applications:Suitable for use in Immunohistochemistry.
• Other applications not tested.
• Recommended Dilutions:Immunohistochemistry: 5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.