DNA repair protein XRCC4 encoded by XRCC4 functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks.
This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination.
Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED).
Alternative splicing generates several transcript variants.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human XRCC4.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa230-310 of human XRCC4 at C-terminal.
