XDH (xanthine dehydrogenase) is a protein coding gene.
Diseases associated with XDH include xanthinuria, type I and xanthinuria.
Among its related pathways are doxorubicin pathway, pharmacokinetics and metabolism.
XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines.
The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.
XDH can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification.
Defects in XDH cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human XDH. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to human XDH.