VCAN is a member of the aggrecan/versican proteoglycan family.
The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix.
This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance.
Mutations in VCAN are the cause of Wagner syndrome type 1.
Multiple transcript variants encoding different isoforms have been found for VCAN.
VCAN (versican) is a protein coding gene.
Diseases associated with VCAN include Wagner syndrome 1 and Wagner syndrome.
Among its related pathways are ECM proteoglycans and cell adhesion-cell-matrix glycoconjugates.
Applications:Suitable for use in Immunohistochemistry and ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:50-1:200ELISA: 1:10,000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human Versican. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa2530-2580 from human Versican.
