84-5608-82　［取扱停止］VEGI 100ul　543707

特徴

• Tumor necrosis factor ligand superfamily member 15 encoded by TNFSF15 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.
• This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells.
• The expression of this protein is inducible by TNF and IL-1 alpha.
• This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6.
• It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells.
• This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.
• Two transcript variants encoding different isoforms have been found for this gene.
• Applications:Suitable for use in Western Blot, Immunofluorescence, and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:200-1:1000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.