84-5608-18　［取扱停止］VATG2 100ul　543670

特徴

• ATP6V1G2 (ATPase H+ transporting V1 subunit G2) is a protein coding gene.
• Among its related pathways are rheumatoid arthritis and mTOR signaling pathway (KEGG).
• ATP6V1G2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells.
• V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
• V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain.
• The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits.
• The V1 domain contains the ATP catalytic site.
• The V0 domain consists of five different subunits: a, c, c', c" and d.
• Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants.
• This encoded protein is one of three V1 domain G subunit proteins.
• ATP6V1G2 had previous gene symbols of ATP6G and ATP6G2.
• Alternatively spliced transcript variants encoding different isoforms have been described.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.