VANGL2 (VANGL planar cell polarity protein 2) is a protein coding gene.
Diseases associated with VANGL2 include neural tube defects and Vangl2-related neural tube defect.
Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Wnt signaling pathway and pluripotency.
The protein encoded by VANGL2 is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea.
The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets.
This protein is also involved in the development of the neural plate.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human VANG2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human VANG2
