USP48 (ubiquitin specific peptidase 48) encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin C-terminal hydrolases.
Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin.
Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Applications:Suitable for use in Immunohistochemistry, ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100-1:300ELISA: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of human USP48. Species Crossreactivity: Mouse, rat
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa600-680 from the Internal region of human USP48.