TTC19 (tetratricopeptide repeat domain 19) encodes a protein with a tetratricopeptide repeat (TPR) domain containing several TPRs of about 34aa each.
These repeats are found in a variety of organisms including bacteria, fungi and plants, and are involved in a variety of functions including protein-protein interactions.
This protein is embedded in the inner mitochondrial membrane and is involved in the formation of the mitochondrial respiratory chain III.
It has also been suggested that this protein plays a role in cytokinesis.
Mutations in TTC19 cause mitochondrial complex III deficiency.
Alternatively spliced transcript variants have been found for TTC19.
TTC19 is a protein coding gene.
Diseases associated with TTC19 include mitochondrial complex Iii deficiency, nuclear type 2 and mitochondrial complex Iii deficiency.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:
Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human TTC19. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to human TTC19.
