TSHZ3 (teashirt zinc finger homeobox 3) encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract.
Consistent with this role, mice in which TSHZ3 has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis.
The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression.
Reduced expression of TSHZ3 and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients.
TSHZ3 is a protein coding gene.
Diseases associated with TSHZ3 include hydronephrosis and endemic Goiter.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human TSH3.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human TSH3.
