TRPV6 (transient receptor potential cation channel subfamily V member 6) is a protein coding gene.
Diseases associated with TRPV6 include prostate cancer and aromatase deficiency.
Among its related pathways are TRP channels and mineral absorption.
TRPV6 encodes a member of a family of multipass membrane proteins that functions as calcium channels.
The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation.
Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine.
TRPV6 is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5).
This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：30ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human TRPV6. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human TRPV6.
