KCNK4 encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily.
The potassium channel subfamily K member 4 homodimerizes and functions as an outwardly rectifying channel.
This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane.
Potassium channel subfamily K member 4 is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons.
Alternate splicing results in multiple transcript variants.
Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human TRAAK. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa310-390 of human TRAAK at C-terminal.
